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 DHT (dihydrotestosterone) is a hormone that plays a key role
in hair loss, particularly male pattern baldness.
In women, DHT-related hair loss typically manifests as diffuse
thinning across the scalp rather than the receding hairlines or
bald spots more common in men.
Here are the
key points about DHT and its effects on hair:
1. DHT is an androgen (male sex hormone) derived from
testosterone. About 10% of testosterone is converted to DHT by
an enzyme called 5-alpha reductase.
2. DHT can bind to receptors on hair follicles in the scalp,
causing them to shrink and become less capable of supporting
healthy hair growth.
3. This leads to a shortening of the hair growth cycle and
eventual miniaturization of hair follicles, resulting in
thinning hair and baldness.
4. DHT is considered the primary cause of male pattern baldness
(androgenetic alopecia), which affects about 50% of men over age
50.
5. While DHT is necessary for some functions like body hair
growth, excessive DHT activity in the scalp leads to hair loss
in genetically susceptible individuals.
6. Treatments for DHT-related hair loss include:
-
DHT blockers like
finasteride
and
dutasteride, which inhibit the 5-alpha
reductase enzyme
-
Minoxidil, which improves blood flow to hair follicles.
(Found in one of the most common brand names
Regaine.)
-
Low-level laser and
red light therapy
-
Hair transplant surgery
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Saw Palmetto is a natural supplement widely used to
treat hair loss, particularly androgenetic alopecia (male
and female pattern baldness)
7. Natural DHT blockers like saw palmetto are sometimes used,
but have less scientific evidence supporting their effectiveness
compared to medications like
finasteride.
8. Genetics play a major role in determining sensitivity to
DHT's effects on hair follicles.
In summary, DHT is a potent hormone that can cause hair follicle
miniaturization and hair loss in susceptible individuals, but
there are treatments available to help counteract its effects.
Related pages:
How to treat
male pattern baldness naturally
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